Biblical to Classical Period (300 BC - 476 AD):
Through their traditional trade routes and communications to the Orient, Arab merchants had nearly exclusive control over the purchase and transport of spices.
About 40 AD, the Greek merchant , Hippalus, realized the winds over the Indian Ocean were seasonal, or monsoonal. Between April and October winds blew from northwest to southeast and reversed between October and April.
Romans develop armada of ships, regularize trade, and break Arab domination of the Indian market.
476 AD Romulus Augustulus deposed and end of the Roman Empire.
Dark Ages (476 - 1095)
Crusades (1095 to ca. 1300)
European Spice Trade:

Marco Polo returned to Venice in 1297
1418 Exploratory Voyages and navigational research sponsored by Prince Henry of Portugal
1486 Diaz of Portugal rounds the Cape of Good Hope
1492 Columbus sails to the New World
1493 Pope Alexander VI divides the world between Spain and Portugal
1494 Treaty of Tordesillas
1498 Vasco de Gamma reaches India by sailing around Africa
1522 Circumnavigation of the world (Magellan, Spain)
1588 Destruction of the Spanish armada
Early in the 17th century, Holland drives Portuguese from the Spice Islands. By 1621 Holland has world control of the nutmeg and clove business.
1824 -- After a long period of fighting the Dutch and English concluded a treaty in which the Dutch retain the East Indian Archipelago (except for the northern part of Borneo) and the English keep India, Ceylon and the Malay peninsula. These empires were to last, virtually intact, for the next nearly 125 years.
The United States -- The U.S. was an active participant in the spice trade, especially pepper, from about 1778 until the beginning of the Civil War in 1861
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Peppers
Scoville Units for some familiar peppers
0 Bell, Sweet Peppers, Pimento
100-1000 Anaheim, New Mexico
1000-1500 Ancho, Cherry
1500-2500 Cascabel, Rocotillo
2500-5000 Jalapeno
5000-15,000 Serrano
30,000-50,000 Cayenne, Tobasco
50,000-100,000 Thai
100,000-300,000 Habanero
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Plant --------- Use
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Geranium --- Dermatitis, relaxation, depression
Lavender --- Antiseptic, respiratory infections, relaxation
Juniper --- Antiseptic, relaxation, aches & pains
Pine --- Asthma, arthritis, depression
Rosemary --- Bronchitis, depression, mental alertness
Ginger --- Bronchitis, arthritis, stimulant
Frankincense --- Coughing, bronchitis
Eucalyptus --- Anti-inflammatory, arthritis, relaxation
Marjoram --- Respiratory infections, relaxation
Mint --- Relaxation